<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, A21T, V31I, S39N, I72V, Q95H, K103R, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, R187K, V201I, T206S, L234I S283G
>AA070a_LH07| codons 1-288
FLDGIDKAQEEHERYHSNWRTMASDFNLPPIVAKEIVANCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGHETAYFLLRLAGRWPVKVIHTDNGSN
FTSAAVKAACWWANVRQEFGIPYNPQSQGVVESMNKELKKIIGQIREQAEHLKTAVQMAV
FIHNFKKKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12V, G16E, E35D, M36I, R41K, R57K, H69K, L89M, I93L  
>AA070a_LH07| codons 1-99
PQITLWQRPLVVIKIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, K11A, V35T, T39K, K43E, K122E, D123S, K166R, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, A272P, K275R, V276I, K281R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, T369A, A371V, I375V, K395R, A400T, E404D, E432D, V435L, N447S, D471E, K476Q, Q480H, H483Q, L491S, K512R, E516D, L517I, S519N, Q524E, K527R, A534S, A554S H221HR
>AA070a_LH07| codons 1-560
PISPIDTVPVALKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRIKNPEMVI
YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKRQKEPPFLWMGYELHPDRWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIRIKQLCRLLRGAKALTDIVPLTEEAE
LELAENREILKTPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEQFKNLKTGKYARKRSA
HTNDVRQLAEVVQKVATESIVIWGKTPKFKLPIQRETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKDPILGAETFYVDGAASRETKLGKAGYVTDRGRQKVVSLTETTNQQTELH
AIQLALQDSGSEVNIVTDSQYALGIIQAQPDRSESDIVNQIIEELIRKEKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Rolland, M Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2 Nature, 2012