Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, A21T, D25E, S39N, L45V, L101I, T112V, T124A, T125A, G134N, I135V, K136R, M154I, D167E, V201I, Q216N, L234I | S283G |
| >AA021a06L| codons 1-288 FLDGIDKAQEEHERYHSNWRTMASEFNLPPVVAKEIVANCDKCQVKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWANVRQEFGIPYNPQSQGVVESINKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKNITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, I15V, E35D, M36I, R41K, R57K, H69K, K70R, L89M |
| >AA021a06L| codons 1-99 PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, K11T, V35T, T39K, K43E, K49R, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, I178M, T200R, Q207A, R211S, K238R, V245E, A272P, K281R, T286A, E291D, V292M, I293V, E297Q, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, T377I, K395R, A400T, T409TA, E432D, N447S, R461K, D471E, Q480H, H483Q, L491S, K512R, L517I, S519N, Q524E, A534S, A554S |
| >AA021a06L| codons 1-560 PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRIKNPEMVI YQYMDDLYVGSDLEIGQHRRKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDMVPLTQEAE LELAENREILKTPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVRQLAEVVQKIAIESIVIWGKTPKFKLPIQRETWETWWTEYWQAAWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAASRETKLGKAGYVTDKGRQKVVSLTETTNQKTELH AIQLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEIVNQIIEELIKKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Rolland, M | Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2 | Nature, 2012 |