<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
  V151I K14R, R20K, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, G193E, V201I, L234I V281M, S283G
>2880| codons 1-288
FLDGIDKAQEEHERYHSNWKAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWANVRQEFGIPYNPQSQGVIESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGEYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCMAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K20R, E35D, M36I, R41K, H69K, L89M, I93L  
>2880| codons 1-99
PQITLWQRPLVTIKIGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, K11T, V35T, T39K, K43E, K122E, D123G, S162Y, K173R, Q174K, D177E, I178M, V179I, Q207T, R211S, K238R, V245E, V276I, Q278H, K281R, T286A, E291D, V292I, I293V, E312T, V317T, I326V, I329V, G335D, Y342F, M357K, R358G, G359S, K366R, A371V, K374R, T377R, K390R, A400T, T403M, A437V, L452R, D471E, Q480H, H483C, L491S, K512R, L517I, Q524E, A534S, A554S  
>2880| codons 1-560
PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRRKNPEMII
YQYMDDLYVGSDLEIGQHRTKIEELRTHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKIKHLCRLLRGAKALTDIVPLTEEAE
LELAENREILKTPVHGTYYDPSKDLVAEVQKQGQDQWTYQIFQEPFKNLKTGKYARKGSA
HTNDVRQLTEVVQRIARESIVIWGKTPKFRLPIQKETWETWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGVETFYVDGAANRETKRGKAGYVTDRGRQKVVSLTETTNQKTELH
AICLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEIVSQIIEELIKKEKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Li, L Genetic characterization and transmitted drug resistance of the HIV type 1 epidemic in men who have sex with men in Beijing, China ARHR, 2013