<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14KR, A21T, A23V, V31I, T112V, T124A, T125A, G134N, I135V, K136R, M154I, D167E, V201I, L234I S283G
>2857| codons 1-288
FLDGIDKAQEEHERYHSNWRTMVSDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWANVRQEFGIPYNPQSQGVVESINKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L19M, E35D, M36I, R41K, H69K, L89M, I93L  
>2857| codons 1-99
PQITLWQRPLVTIKIGGQMKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, V35T, T39K, K122E, D123S, I135T, I142V, T165I, K173V, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, A371V, K390R, K395R, A400T, E432D, N447S, D460N, D471E, Q480H, H483Y, G490E, L491S, K512R, L517I, S519N, Q524E, I526V, A534S, A554S, I556V  
>2857| codons 1-560
PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMIKILEPFRVKNPEIVI
YQYMDDLYVGSDLEIGQHRIKIEELRAHLLSWGLTTPDKKHQKEPPFLWMGYELHPDRWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKIKQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKTPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEQFKNLKTGKYARKRSA
HTNDVRQLTEVVQKIATESIVIWGKTPKFRLPIQRETWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIVGAETFYVDGAASRETKLGKAGYVTNRGRQKVVSLTETTNQKTELH
AIYLALQDSESEVNIVTDSQYALGIIQAQPDRSESEIVNQIIEELVKKEKVYLSWVPAHK
GIGGNEQVDKLVSSGVRKVL

References
Author Title Citation
Li, L Genetic characterization and transmitted drug resistance of the HIV type 1 epidemic in men who have sex with men in Beijing, China ARHR, 2013