<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, K14R, V31I, V32I, A49V, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, G193E, V201I, L234I S283G, D286N
>2828| codons 1-288
FLDGIDKAQEDHERYHSNWRAMASDFNLPPIIAKEIVASCDKCQLKGEVMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWANVRQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGEYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQNED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    G16A, E35D, M36I, R41K, E65D, H69K, L89M  
>2828| codons 1-99
PQITLWQRPLVTIKIAGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIDICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, K11T, D17DE, V35T, T39R, K43E, V60I, S68G, K122E, D123S, I135R, S162C, K173R, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, K275R, K277R, T286A, E291D, V292I, I293V, E312T, V317T, I326V, G335D, M357T, G359S, K388R, K390R, A400T, N447S, D471E, Q480H, L491S, V493L, K512R, L517T, S519N, Q524E, A534S, I556V  
>2828| codons 1-560
PISPIDTVPVTLKPGMEGPKVKQWPLTEEKIKALTEICREMEEEGKISKIGPENPYNTPI
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRRKNPEMVI
YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIRVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKTPVHGTYYDPSKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYARTRSA
HTNDVKQLTEAVQKIATESIVIWGKTPRFRLPIQKETWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGAETFYVDGAASRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH
AIHLALQDSGSELNIVTDSQYALGIIQAQPDRSESETVNQIIEELIKKEKVYLSWVPAHK
GIGGNEQVDKLVSAGVRKVL

References
Author Title Citation
Li, L Genetic characterization and transmitted drug resistance of the HIV type 1 epidemic in men who have sex with men in Beijing, China ARHR, 2013