Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E10D, V32I, L45I, I72V, L101I, K103R, T112K, T124A, K156N, D167E, V201I, I220V, S230N, K240R |
| >2820| codons 1-288 FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVIAKEIVASCDKCQIKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILRLAGRWPVKKIHTDNGSN FTSATVKAACWWAGIKQEFGIPYNPQSQGVVESMNNELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKVQNFRVYYRDNRDPLWKGPAR LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19Q, N37S, R41K, L63P |
| >2820| codons 1-99 PQITLWQRPLVSIKVGGQQKEALLDTGADDTVLEEMSLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K238N | I5V, V118I, D123E, I135V, F214L, V261I, I293V, D324E, I329L, M357A, A376T, V381I, T386I, A400T, T403I, E449D, T477M, Q507H, Q509K, K512R, V548I, A554N |
| >2820| codons 1-560 PISPVETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDNWT VQPIVLPEKDSWTVNDIQKLIGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKELIAELQKQGQGQWTYQIYQEPFKNLKTGKYARARGA HTNDVKQLTEAVQKITTESIIIWGKIPKFKLPIQKETWETWWIEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRDTKLGKAGYVTDRGRQKVVSLTDTTNQKMELQ AIHLALQDSGLEVNIVTDSQYALGIIHAKPDRSESELVSQIIEQLIKKEKVYLAWVPAHK GIGGNEQIDKLVSNGIRKVL |
References
| Author | Title | Citation |
| Li, L | Genetic characterization and transmitted drug resistance of the HIV type 1 epidemic in men who have sex with men in Beijing, China | ARHR, 2013 |