Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ED_V41 | ED_V41 | Venezuela | 1999 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ IDV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14R, I15V, G16E, N37T, P39S, L63H, H69K |
| >ED_V41| codons 1-99 PQITLWQRPLVTIRVEGQLKEALLDTGADDTVLEEMTLSGRWKPKMIGGIGGFIKVRQYD QIHIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K122E, S162C, Q207E, R211K, F214L |
| >ED_V41| codons 36-250 EICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIP HPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKG SPAIFQCSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGLT TPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKD |
References
| Author | Title | Citation |
| Delgado, E | Analysis of HIV type 1 protease and reverse transcriptase sequences from Venezuela for drug resistance-associated mutations and subtype classification: a UNAIDS study. | ARHR, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |