Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ED_V7 | ED_V7 | Venezuela | 1999 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | T215S | S68G, K122E, I135T, A158S, I178M, T200E, R211K, V245MT |
| >ED_V7| codons 36-250 EICTEMEKEGKISKIGPENPYNTPVFAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIP HPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKG SPSIFQSSMTKILEPFRKQNPDMVIYQYVDDLYVGSDLEIGQHREKIEELRQHLLKWGFS TPDKKHQKEPPFLWMGYELHPDKWTVQPIMLPEKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, K14R, E35D, R41K, L63LH, I64V, I93L |
| >ED_V7| codons 1-99 PQITLWQRPIVTIRIGGQLKEALLDTGADDTVLEDMNLPGKWKPKMIGGIGGFIKVRQYD QIHVEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Delgado, E | Analysis of HIV type 1 protease and reverse transcriptase sequences from Venezuela for drug resistance-associated mutations and subtype classification: a UNAIDS study. | ARHR, 2001 |
| Gonzales, MJ | Extended spectrum of HIV-1 reverse transcriptase mutations in patients receiving multiple nucleoside analog inhibitors. | AIDS, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |