Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TCDD-13 | TCDD-13_1 | Zimbabwe | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 13 |
| 2 | 3TC+AZT+SQV | 69 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12TS, I15V, L19LI, M36I, R41K, L63LAPV, H69K, V82I, L89LM, I93L | L24L* |
| >TCDD-13_1| codons 3-99 ITLWQRPLVSIKVGGQIKEAL*DTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQI VIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39E, S48T, K122E, D123NS, S162SN, K173V, Q174K, D177E, T200A, Q207A |
| >TCDD-13_1| codons 29-242 EKIKALTEICEEMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFW EVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDENFRKYTAFTIPSINNETPGIRYQYNV LPQGWKGSPAIFQNSMTKILEPFRVKNPEIVIYQYMDDLYVGSDLEIGQHRAKIEELRAH LLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQ |
References
| Author | Title | Citation |
| Kantor, R | HIV-1 subtype C reverse transcriptase and protease genotypes in Zimbabwean patients failing antiretroviral therapy. | ARHR, 2002 |
| Johnston, E | High frequency of syncytium-inducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment. | J Virol, 2003 |
| Kassaye, S | Envelope coreceptor tropism, drug resistance, and viral evolution among subtype C HIV-1-infected individuals receiving nonsuppressive antiretroviral therapy. | JAIDS, 2009 |