<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74I, M184V, L210W, T215Y D67G, V75T, K219D L100LI, K103N, Y181YC, G190GA V108I K20R, V35I, E44D, S68G, K122P, I135V, Q174R, D177E, G196E, R211K, D218E, L228H, T286A, I293V, E297A, S322A, L325I, M357T, G359S, A371V, I382V V261VIM
>206762| codons 1-400
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTELEKDGKISKIGPENPYNTPV
FAIKKKGGTKWRKITDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTILDVGDAYFSVPL
DPDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPEIVI
CQYVDDLYVASDLEIEQHRTKIEELRQHLWKWGFYTPEDKHQKEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLMGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVPLTAEAE
LELAENREILKEPVHGVYYDPAKDIIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTRSA
HTNDVKQLTEVVQKIATESIVVWGKTPKFKLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I54V, V82A L24I, Q58E, G73C L10I, K20R, E35D, M36I, N37D, R41K, K55KR, R57RK, I62V, L63P, A71V, I72LV, I93IL  
>206762| codons 1-99
PQITLWQRPIVTIKIGGQLREALIDTGADDTVLEDIDLPGKWKPKIIGGIGGFVRVKEYD
QVPIEICGHKVVCTVLVGPTPANIIGRNLLTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012