<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
206604 206604 Argentina 2007 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, T215F K219Q K101E, K103S, G190A   E28K, K32E, V35I, T39A, V60I, D177N, T200A, R211K, L228F, V245K, T286A, E297A, D324E, I326V, R356K, G359S, A360T, K390R, E399D  
>206604| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALIEICAELEKEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKSKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPNIVI
YQYMDDLYVASDLEIGQHRAKIEELRQHLLKWGFFTPDQKHQKEPPFFWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVIPLTAEAE
LELAENREILKEPVHGVYYDPSKELVAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMRST
HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I50L G73S E34K, E35D, M36MI, N37D, K45R, I62V, L63P, I64V, V77I, I93L  
>206604| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLKDIDLPGRWKPRMIGGLGGFIKVRQYD
QVPVEICGHKAISTVLIGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012