<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y   Y181C A98AG K20R, E28EG, V35L, T39TA, E44D, K49KR, K101Q, K104R, V118I, K122E, D123E, I135V, K173R, E203K, Q207E, R211K, L228H, V245E, A272P, I293V, G333E, G359S, A371V, S379G, T386V  
>206357| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTGEKIKALLEICAELEKDGKISRIGPENPYNTPV
FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLQKKRSVTVLDVGDAYFSIPL
DEEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRRQNPDIVI
CQYVDDLYVGSDLEIGQHRTKIKELREHLWKWGFYTPDKKHQKEPPFHWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQEQGQWTYQIYQEPFKNLKTGKYARMRSA
HTNDVKQLTEVVQKIATEGIVIWGKVPKFKLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A L24I, K43T, F53L L10I, I15V, K20R, E35D, M36I, N37D, K55R, R57RK, I62V, L63P, T74A  
>206357| codons 1-99
PQITLWQRPIVTIKVGGQLREALIDTGADDTVLEDIDLPGRWTPKLIGGIGGLVRVKQYD
QVPIEICGHKAIGAVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012