<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, K70R, L210W, T215Y D67H, V75VA, K219DE Y181C, G190A   V35VI, E44D, V60I, K66KR, S68N, T69N, K101Q, V118I, K122E, D123E, I135T, R172RK, I178IM, T200A, E203EG, R211K, D218E, L228H, V245K, A272P, K277R, I293V, E297K, A304E, V317A, Q334L, M357I, A360V, I375V, T377M, S379C, K390R, K395R, E399D  
>205968| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELEKDGKISKIGPENPYNTPI
FAIKKRHNNRWRKLADFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSIPL
DEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDMVI
CQYMDDLYVASDLEIGQHRAKIGELRQHLWKWGFYTPEEKHQKEPPFHWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTKEAE
LELEENREILKEPVHGAYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKYARIRGV
HTNDVKQLTEAVQKVAMECIVIWGKTPKFRLPIQRETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, G48V, I50V, I54A, V82A L33F, K43T L10I, T12I, I13V, L63A, H69Y, K70E, A71V, I72V, V77I, I93L  
>205968| codons 1-99
PQITLWQRPIVIVKIGGQLKEALLDTGADDTVFEEMNLPGRWTPKLIVGVGGFAKVRQYD
QIAIEICGYEVVGTVLIGPTPANIIGRNLLTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012