<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, L210W, T215Y K219R K101E, K103RS, G190AS   E28K, V35I, K43N, V60I, V118I, K122E, G196E, Q197K, A272P, K281R, V292VI, I293IV, E297KR, S322A, D324DE, M357T, T369A  
>205791| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIKALIEICTELENEGKISKIGPENPYNTPI
FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLEKSKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLYVSSDLEIEKHRTKIEELRQHLWRWGFYTPDRKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTEIVPLTREAE
LELAENREILKEPVHGVYYDPAKELIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTRGA
HTNDVKQLAEAVQKIATESIVIWGKTPKFKLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, I84V, L90M   L10I, I13IV, I15V, Q18K, K20M, E35D, M36I, R41K, Q61N, I62V, L63P, I66IV, T74A, L89I  
>205791| codons 1-99
PQITLWQRPIVTVKVGGKLMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD
NVPIEVCGHKAIGAVLVGPTPVNVIGRNIMTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012