<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, V75M, M184V, L210W, T215Y K219N L100I, K103N   T7TA, M16V, V21I, E28K, K32E, T39K, K43E, E44A, K73M, R83RK, D86N, K102R, V111I, V118I, K122E, A158S, V179I, V189VI, H208Y, R211K, L228H, A288S, V292I, I293V, E297K, S322T, G335C, G359NS, A371V, A376S, K390R, E399D K395T, W398W*
>205729| codons 1-399
PISPIEAVPVKLKPGVDGPKIKQWPLTKEKIEALVEICKELEEAGKISKIGPENPYNTPV
FAIKKKNSDKWRMLMDFRELNKKTQNFWEVQLGIPHPAGIKRNKSVTVLDIGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQNPDIII
YQYVDDLYIGSDLEIGQHRTKIEELRQYLWKWGFYTPDNKHQKEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKSLTEIVPLTKEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQCQWTYQIYQEPFKNLKTGKYARMRSA
HTNDVKQLTEVVQKISTESIVIWGKTPKFRLPIQTET*D

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I47V, I54M, L76V, I84V, L90M L10F, G48E, F53L, L89V Q7R, I15V, Q18H, L19V, K20T, E34K, E35D, M36I, K55R, R57K, L63P, A71IV, V77I, I85V  
>205729| codons 1-99
PQITLWRRPFVTIKVGGHVTEALLDTGADDTVLKDINLPGRWKPKLVEGIGGLMRVKQYD
QIPIEICGHKVIGTVVIGPTPVNVVGRNVMTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012