<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67DN, K70KR, M184V, T215F K219E     V35VI, K122P, D123DE, D177E, V179I, T200TA, Q207E, L228LH, E233EK, A272P, T286A, I293IV, P294T, E297Q, D324E, I329V, Q334D, R356RK, R358RK, A360AV, A371AV, A376V, S379C, G384GE, K390R, Q394L, E399D E53EK, W153W*
>204240| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELEKEGKISKIGPKNPYNTPV
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DPEFRKYTAFTIPSINNETPGIRYQYNVLPQG*KGSPAIFQSSMTKILEPFRKQNPEIII
YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFFTPDEKHQKEPPFHWMGYKLHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVVTLTQEAE
LELAENREILKEPVHGVYYDPSKELIAEVQKQGDGQWTYQIYQEPFKNLKTGKYAKMKGV
HTNDVKQLTEVVQKIVTECIVIWEKTPKFRLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48GV, L90LM   L10V, T12TK, I15IV, K20KR, E34EQ, E35D, M36IV, N37ND, R41K, R57K, D60DE, Q61D, I62IV, L63LP, A71AV, T74TS, V77VI, I93L  
>204240| codons 1-99
PQITLWQRPVVKIKVGGQLREALLDTGADDTVLQDVDLPGKWKPKMIVGIGGFIKVKQYE
DVPIEICGHKVIGSVLIGPTPVNIIGRNLMTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012