<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70R     A98AG K20R, V35T, T39R, V90I, D121HY, K122E, I135T, D177E, E203EK, Q207E, R211T, F214FL, V245K, T286A, E291D, V292I, I293V, E297K, A304E, E312D, I329L, G335D, R356K, M357K, R358K, G359S, A360T, T377M, T386I, K390R, Q394H  
>203362| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICREMEKEGKISKIGPENPYNTPV
FAIKKKDSTRWRKLVDFRELNKRTQDFWEIQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI
YQYMDDLYVGSDLEIGQHRTKIKELREHLLTWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTKEAE
LELEENREILKDPVHGVYYDPSKDLIAELQKQGQDQWTYQIYQEPFKNLKTGKYAKKKST
HTNDVKQLTEAVQKIAMESIVIWGKIPKFRLPIHKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L5LF, L10LP, I13V, G16E, E35D, M36I, R41K, L63V, H69K, L89M, T91V  
>203362| codons 1-99
PQITFWQRPPVTVKIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNMLVQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012