<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, I84V   I3V, I13V, K20T, E35D, M36V, R41K, I62V, L63P, A71T, I72R, P79S R8Q
>203270| codons 1-99
PQVTLWQQPLVTVKIGGQLTEALLDTGADDTVLEDVNLPGKWKPKIIGGIGGFVKVRQYD
QVPIEICGHKTRGTVLVGSTPVNVIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y K219E K101E, Y181C, G190A   E6D, V8VA, K20R, K22KR, V35VI, T39A, K64R, K66R, V118I, K122E, F171Y, Q174R, D177E, T200A, E203K, Q207D, R211K, D218E, V261VI, R284K, T286A, E297AV, I326IV, I329L, F346Y, M357T, T386TI, K390R E40E*, I94IM
>203270| codons 1-400
PISPIDTAPVKLKPGMDGPRVRQWPLTEEKIKALIEICA*LEKEGKISKIGPENPYNTPV
FAIRKRNSTKWRKVVDFRELNKRTQDFWEVQLGMPHPAGLEKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPYRKRNPEIVI
CQYVDDLYVASDLEIGQHRAKIKELRDHLWKWGFYTPEEKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLIGKLNWASQIYAGIKVKQLCKLLKGAKALTEVIPLTVEAE
LELAENREILKEPVHGVYYDPSKDLVAELQKQGQGQWTYQIYQEPYKNLKTGKYARTRGA
HTNDVKQLTEAVQKIATESIVIWGKIPKFRLPIQKETWEA

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012