<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, M184V, T215Y   Y181C   T39A, V90I, K122E, I135LM, I142T, K166R, Q174A, T200A, A272P, K277R, E297K, D324E, P345Q, K347KR, R356RK, G359S, A376S, T377Q, T386I, K390R  
>202025| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKVVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSMNNETPGTRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKANPDIVI
CQYVDDLYVGSDLEIGQHRAKIEELRQHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTKEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGQGQWTYQIYQEQFRNLKTGKYAKMRSA
HTNDVKQLTEAVQKISQESIVIWGKIPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I84V, L90M L10F, Q58QE, N88G I15V, Q18H, K20V, M36I, K55R, I62V, L63P, A71T, I72V, I85V  
>202025| codons 1-99
PQITLWQRPFVTIKVGGHLVEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFIRVREYD
QVPIEICGHKTVGTVLVGPTPVNVVGRGLMTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012