<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, D67N, K70R, M184V, T215F V75M, K219E     P1L, V35T, V60I, V106I, V118I, K122E, I135T, R211T, F214L, E248D, A272P, K275R, Q278H, K281R, A288T, V292I, I293V, E297K, I341V, R356RK, M357V, R358K, G359S, V365I, L368M, T386I, K390R, A400T  
>200259| codons 1-400
LISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSIPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRTKIEELRQHLLTWGLFTPDEKHQKEPPFLWMGYELHPDKWT
VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYPGIRVKHLCRLLRGTKTLTEIVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQVYQEPFKNLKTGKYAKVKSA
HTNDIKQMTEAVQKIATESIVIWGKIPKFRLPIQKETWET

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47V, I54V, V82A, L90M F53L, Q58E, G73S L10IV, I15V, L19I, K20R, E35D, M36I, N37D, R57K, D60E, Q61N, I62V, L63P, A71V, I72M  
>200259| codons 1-99
PQITLWQRPVVTIKVGGQIREALLDTGADDTVLEDIDLPGRWKPKIVGGIGGLVKVKEYE
NVPIEICGHKVMSTVLVGPTPANIIGRNLMTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012