<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74I, M184V, T215F     A98G K11R, V35I, T39A, K122E, D123N, I135L, A158S, H208Y, A272P, T286A, E297K, I329V, K350R, R356K, M357S, A376S, T386I, Q394L  
>200121| codons 1-399
PISPIETVPVRLKPGMDGPKVKQWPLTEEKIKALIEICAEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRTKIEELRQYLLRWGFFTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGQGQWTYQIYQEPFKNLRTGKYAKSRGA
HTNDVKQLTEAVQKISTESIVIWGKIPKFKLPILKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82T, I84V L33F, G73S L10V, I13V, K14R, I15V, Q18L, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62IV, L63P, A71AT, I72T, I93L T74TI
>200121| codons 1-99
PQITLWQRPVVTVRVGGLLREALLDTGADDTVFEDIDLPGKWKPKIIGGIGGFVKVKQYD
NVPIEICGHKTTSIVLVGPTPTNVIGRNLLTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012