<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L210W, T215Y   V106A F227L V35T, T39L, S68G, V90I, V118I, K122KE, T200A, E203A, H208Y, K223Q, L228HR, A272P, K281R, L283I, A288T, P294S, E297K, E312EG, I329V, F346Y, R356K, G359S, K366R, T386TI, Q394L, K395KR, E399D  
>199633| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICLELEKEGKISKIGPENPYNTPV
FAIKKKDGTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSATVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRAKIAELRQYLWRWGFYTPDKKHQQEPPLRWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLIRGTKTLTEVISLTKEAE
LELAENREILKGPVHGVYYDPSKDLIAEVQKQGQGQWTYQIYQEPYKNLKTGKYAKMRSA
HTNDVRQLTEAVQKIATESIVIWGKIPKFKLPILRETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N, M46I F53FL, N88D L10X, I13IV, I15AV, K20T, E35D, M36I, R41K, R57K, Q61N, L63A, A71V, T74S, I85V, I93L  
>199633| codons 1-99
PQITLWQRPXVTVKVGGQLTEALLDTGADNTVLEDINLPGKWKPKIIGGIGGLIKVKQYD
NIAIEICGHKVIGSVLVGPTPVNIVGRDLLTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012