<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, Y115F, M184V, T215F   K101P, K103N   E28R, K32E, V35T, T39A, K49E, V118I, K122E, D123N, I135V, I142V, Q174QKR, V179IT, G196GE, I202V, R211K, L228LM, V245MT, E248ED, A272P, L283I, E297R, S322ST, I329L, Q334E, M357T, A376T, K390R, Q394L D177DGNS
>199339| codons 1-398
PISPIETVPVKLKPGMDGPKVKQWPLTREKIEALTEICAELEKEGKISEIGPENPYNTPV
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLPKNKSVTVLDVGDAFFSIPL
DENFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPSITI
YQYVDDLYVGSDLEIEQHRTKVEELRQHLLKWGFFTPDKKHQKEPPFMWMGYELHPDKWT
VQPITLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGTKALTEVIPLTREAE
LELAENREILKEPVHGVYYDPTKDLIAELQKQGEGQWTYQIYQEPFKNLKTGKYARTRGA
HTNDVKQLTEAVQKITTESIVIWGKTPKFRLPILKETW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A, L90M V11I, L33I, G73S L10I, I15V, L19I, K20R, E35D, M36I, N37DE, K55R, R57K, D60E, Q61D, I62V, L63P, A71V, I72IFLM, I85V  
>199339| codons 1-99
PQITLWQRPIITIKVGGQIREALLDTGADDTVIEDIELPGRWKPKLIGGIGGFVRVKQYE
DVPIEICGHKVMSTVLVGPTPANIVGRNLMTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012