<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210LW, T215F N348I K101AE, G190A   E28A, A98S, V118VI, K122E, D123E, I135T, K166R, V179I, Q207E, V245K, A272P, K277KR, A288S, I293V, E297A, I329V, T338S, I341F, M357MIT, T369V, S379G, T386I, K390KR  
>198379| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTAEKIKALVEICTELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLEKKKSVTVLDVGDAYFSIPL
DEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIII
YQYVDDLYVASDLEIGQHRTKIEELREHLWRWGFFTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKSLTEVVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGQGQWSYQFYQEPFKILKTGKYARTRGA
HTNDVKQLVEAVQKIATEGIVIWGKIPKFRLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N, L90LM N88D L10V, I15V, G17E, K20RT, E35D, M36I, N37K, R41K, K45R, R57K, Q61D, L63LP, I72R, V75VI, I93IL  
>198379| codons 1-99
PQITLWQRPVVTIKVGEQLTEALLDTGADNTVLEDIKLPGKWKPRMIGGIGGFIKVKQYD
DIPIEICGHKARGTILVGPTPVNIIGRDLMTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012