<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, M184V T215L, K219Q V106A   V35M, V60I, V90I, K101Q, D123E, I135T, T139R, S162HY, Q174QR, D177E, E194D, G196GE, I202V, V245E, A272P, K277R, T286A, A288G, I293V, E297K, Q334E, K350R, M357KN, A360T, K388KN  
>198108| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICTEMEKEGKISKIGPENPYNTPI
FAIKKKNSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLQKKKSATVLDVGDAYFSVPL
DKEFRKYTAFTIPSTNNERPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKRNPEIVI
YQYVDDLYVGSDLDIEQHRTKVEELRQHLLRWGFLTPDQKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKGLTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGEGQWTYQIYQEPFKNLRTGKYARNRGT
HTNDVKQLTEAVQKIATESIVIWGKTPNFKLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, L90M   L10LV, I13V, K20T, E35D, M36I, N37D, K55R, R57RK, L63P, A71T  
>198108| codons 1-99
PQITLWQRPVVTVKIGGQLTEALLDTGADDTVLEDIDLPGRWKPKLIGGIGGFIRVKQYD
QIPIEICGHKTIGTVLVGPTPVNIIGRNLMTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012