<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A, L90M   L5LI, W6LS, Q7QH, L10V, I15V, G16E, L19V, K20R, E35D, M36I, P39S, R41K, K55R, R57K, Q61N, L63C, E65ED, A71V, I72V, I93L  
>197469| codons 1-99
PQITISHRPVVTIKVEGQVREALLDTGADDTVLEDINLSGKWKPKLIGGIGGFVRVKQYD
NICIDICGHKVVGTVLVGPTPANIIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V, T215TFIS K219Q Y188L, G190GA   T39A, V60VI, K64H, T69TN, D123E, D177E, V179VI, E203K, Q207E, L228H, A272P, T286P, K287R, I293V, E297R, S322T, M357S, D364E, K366R, K390R, Q394L, E399D  
>197469| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAEMEKEGKISKIGPENPYNTPI
FAIHKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIII
YQYVDDLLVASDLEIGQHRTKIKELREHLLRWGFSTPDQKHQKEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGPRALTEVVPLTREAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARSRGA
HTNEVRQLTEAVQKIATESIVIWGKTPKFRLPILKETWD

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012