<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74LI, M184V, T215Y   G190A A98G V35T, D123E, I135L, I142IT, L210LS, R211K, A272S, V276I, Q278E, K281R, A288T, T296S, E297K, Q334N, G335GS, R356K, K366R, K390R, Q394L, E399D  
>196693| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSLNNETPGTRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVASDLEIGQHRTKIEELRQHLSKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKIKELCRLLRGTKTLTEVIPLSKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGNSQWTYQIYQEPFKNLKTGKYAKMRGA
HTNDVRQLTEAVQKIATESIVIWGKTPKFRLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, Q18QL, L19LM, M36I, R41K, R57K, Q61N, L63P, I93L  
>196693| codons 1-99
PQITLWQRPLVTIKVGGLMKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVKQYD
NIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012