<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T215F V75VAIT Y181GV   K20KR, E28K, K32E, V35T, T39A, V60I, V118I, K122E, I135V, I142V, K166R, R172RK, V179I, L210F, D218E, A272P, K275Q, V276VI, K277R, T286A, I293V, P294S, E297K, R356K, K366R, Q394L, E399D  
>196628| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTKEKIEALTEICAELEKEGKISKIGPENPYNTPI
FAIKKKNSTKWRKLTDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQSSMTRILEPFKKQNPDIII
VQYMDDLYVGSDLEIGQHRTKIEELRQHLFRWGFFTPEKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIQIRQLCKLLRGAKALTEVVSLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMRGA
HTNDVRQLTEAVQKIATESIVIWGKTPKFKLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I54V, V82C, L90M   L10I, Q18E, K20R, E21EG, E35D, M36I, R41K, R57K, Q61N, L63S, E65D, I72T, T74S, L89M, I93L  
>196628| codons 1-99
PQITLWQRPIVTIKIGGELRGALLDTGADDTILEDINLPGKWKPKIIGGIGGFVKVKQYD
NISIDICGHKATGSVLVGPTPCNIIGRNMMTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012