<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L210W, T215Y   Y181C   E28K, V35MT, K43E, K49R, K101Q, V118I, D123E, I135T, I178M, R211RK, L228R, Q242QH, A272P, K281R, L283I, I293V, E300ED, D320E, Q334N, G335S, T386I, K390R, Q394L, E399D  
>194888| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIKALTEICTELEEEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSIPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVI
CQYMDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPDKKHQKEPPFRWMGYELHPDKWT
VHPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLIRGTKALTEVVPLTEEAD
LELAENREILKEPVHGVYYEPSKDLIAEIQKQGNSQWTYQIYQEPFKNLKTGKYARMRGA
HTNDVKQLTEAVQKIATESIVIWGKIPKFRLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47IV, I54V, L76V, V82A K43T, Q58QE L10IV, I15V, Q18E, L19LI, K20R, E35D, M36I, R41K, K55KR, R57K, D60E, Q61N, I62V, L63P, A71AV, L89M, I93IL  
>194888| codons 1-99
PQITLWQRPVVTIKVGGEIREALLDTGADDTVLEDINLPGKWTPKIVGGIGGFVRVKEYE
NVPIEICGHKVIGTVVVGPTPANIIGRNMLTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012