<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T215Y   K103N   V35VI, K101Q, I135L, I142IT, D177N, I178M, V245M, A272P, K281R, A288S, V292I, I293V, E297K, G333E, A371V, I375V, A376S, T386I, K390R, Q394S  
>191242| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSLNNETPGTRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPNMVI
YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKSLTEIVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQEQGQWTYQIYQEPFKNLKTGKYARMRGA
HTNDVKQLTEVVQKVSTESIVIWGKIPKFRLPISKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M   I15IV, K20I, E35N, M36I, R41K, R57K, D60E, Q61D, I62IV, L63P, A71V, T74S, I93L  
>191242| codons 1-99
PQITLWQRPLVTIKVGGQLIEALLDTGADDTVLENINLPGKWKPKMIGGIGGFIKVKQYE
DVPIEICGHKVIGSVLVGPTPVNIIGRNLMTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012