<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V V75I K103N P225H K49R, V60VI, K102R, V118I, K122E, I132L, I135V, I178ILM, T200A, F214L, A272P, L283I, R284K, I293V, E297K, I329L, Q334S, R358K, T377M, I382T, K390R, Q394L, E399D D177S
>190350| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLKRNKSVTVLDVGDAYFSIPL
DEDFRKYTAFTLPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPSMVI
YQYVDDLYVGSDLEIGQHRAKIEELRQHLLRWGLTTPDKKHQKEHPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIKGTKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGSGQWTYQIYQEPFKNLKTGKYARMKGA
HTNDVKQLTEAVQKIAMESIVTWGKTPKFRLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12M, I15V, E35D, M36I, N37D, R41K, R57K, Q61D, L63GISV, E65D  
>190350| codons 1-99
PQITLWQRPLVMIKVGGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVKQYD
DIVIDICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012