<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184MV, T215DY   K101E, Y181C, G190GA A98AG, V108VI V35M, T39A, K49R, V90I, V106VI, K122E, I132V, I135V, T200A, E204D, L210LF, K223Q, L228R, V245T, A272P, K281KR, L283LI, V292I, I293V, E297K, I329L, A376AT, T377L, K390KR, Q394L, E399D  
>189562| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICAEMEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPGGLEKKKSITILDVGDAYFSVPL
DEDFRKYTAFTVPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
CQYVDDLYVASDLEIGQHRAKIEDLRQHLFRWGFYTPDKKHQQEPPFRWMGYELHPDKWT
VQPITLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLIRGTKALTEIVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA
HTNDVKQLTEAVQKITLESIVIWGKTPKFRLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, L90M   L10I, T12P, K14R, I15V, G16E, K20M, E35N, M36I, N37E, P39Q, R41K, R57K, D60E, Q61D, I62V, A71V, I72T, I93L  
>189562| codons 1-99
PQITLWQRPIVPIRVEGQLMEALLDTGADDTVLENIELQGKWKPKMIGGIGGFVKVKQYE
DVLIEICGHKVTGTVLVGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012