<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
JS14 JS96107 Luxembourg 1995 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT+DDC NA
2 3TC+AZT+SQV 24

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y       V35I, K122E, D123S, S162Y, E169D, K173A, Q174K, I178L, R211K, V245Q, E248D  
>JS96107| codons 25-252
PLTEEKIKALIEICTELEKEGKISKIGPENPYNTPVFAIKKKNSDKWRKLVDFRELNKRT
QDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRY
QYNVLPQGWKGSPAIFQYSMTKILDPFRAKNPDLVIYQYVDDLYVGSDLEIGQHRTKIEE
LRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWTVQPIQLPDKDSW

References
Author Title Citation
Servais, J Comparison of DNA sequencing and a line probe assay for detection of human immunodeficiency virus type 1 drug resistance mutations in patients failing highly active antiretroviral therapy. J Clin Microbiol, 2001
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005