<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, L210W, T215Y   L100I, K103N   V35LQ, E36D, K43Q, K104R, V118I, D123E, E138Q, K166R, R211K, L228R, A272P, L283I, P294A, E297K, I329V, K350R, R356K, K366R, T397I, E399D  
>188365| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALQDICTELEQEGKISKIGPENPYNTPV
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNRSVTVLDVGDAYFSIPL
DKEFRKYTAFTIPSINNQTPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPDKKHQKEPPFRWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGTKALTEVIALTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGQGQWTYQIYQEPFKNLRTGKYAKMRGA
HTNDVRQLTEAVQKIATESIVIWGKTPKFKLPIQKEIWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47V, I54V, L76V, V82A   L10I, I15V, G16GA, K20R, E35D, M36I, N37D, R41K, R57K, Q61D, I62V, L63P, I64V, A71V, I85V, I93L  
>188365| codons 1-99
PQITLWQRPIVTIKVAGQLREALLDTGADDTVLEDIDLPGKWKPKIVGGIGGFVKVKQYD
DVPVEICGHKVIGTVVVGPTPANIVGRNLLTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012