<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74IV, M184MV, L210L*W, T215F V75S, N348I Y181C   K20R, K43KE, S68G, V106I, V118I, K122E, D123E, I178L, V179I, F214L, H221Y, A272P, K281R, R284RK, T286TA, I293V, P294Q, E297R, M357T, A371AV, A376T, T386I, K390R, Q394L, E399D  
>187827| codons 2-399
ISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEEEGKISKIGPENPYNTPVF
AIKKKDGTKWRKVSDFRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSIPLD
EEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDLIIC
QYVDDLYVGSDLEIGQHRTKIEELRQHLWRWGLFTPDKKYQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLKGAKALTEVVQLTREAEL
ELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKILKTGKYARTRGAH
TNDVKQLTEVVQKITTESIVIWGKIPKFRLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, L90M V11VI, G73S L10I, I13V, I15V, K20I, E35N, M36I, N37D, R41K, D60E, Q61D, L63P, A71V, I72R  
>187827| codons 1-99
PQITLWQRPIITVKVGGQLIEALLDTGADDTVLENIDLPGKWKPKMIGGIGGFVKVRQYE
DIPIEICGHKVRSTVLVGPTPANIIGRNLMTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012