<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, Y115F, M184V, T215Y   K103S, Y181YC, G190A V179VD V21I, V35T, T39E, V60I, S68SG, K122E, I135T, K173AT, Q174K, N175Y, D177E, Q197E, T200K, Q207E, R211K, H221HY, V245Q, A272P, K275R, K277R, Q278H, T286A, E291D, V292I, I293V, E297K, Q334H, G335D, R356K, G359S, A371V, I375V, T377Q, K390R, E399D  
>187729| codons 1-399
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICEEMEKEGKISKIGPENPYNTPI
FAIKKKDGTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKSKSVTVLDVGDAFFSVPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKYPEIDI
CQYVDDLYVASDLEIGEHRKKIEELREHLLKWGFYTPDKKYQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVRHLCKLLRGAKALTDIVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRSA
HTNDVKQLTEVVQKVAQESIVIWGKTPKFRLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15IV, K20R, E35D, M36I, R41K, D60E, Q61E, C67E, H69K, L89M  
>187729| codons 1-99
PQITLWQRPLVTIKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE
EILIEIEGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012