<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74I, L210W, T215F K219W Y188L V179E, K238N K43E, V106I, V118I, D123E, I135IT, R172K, I202V, A272P, K277R, T286A, I293IV, E297R, V317A, G333E, P345T, M357T, K385KR, T386I, K390R  
>187443| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEEGKISKIGPENPYNTPV
FAIKKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSIPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIEI
YQYMDDLLVGSDLEIGQHRTKVEELRQHLWRWGFFTPDWKHQKEPPFLWMGYELHPDNWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVVPLTREAE
LELAENREILKEPVHGAYYDPSKDLIAEIQKQEQGQWTYQIYQETFKNLKTGKYARTRGA
HTNDVKQLTEAVQKIATESIVIWGRIPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48A, I54V, V82A, I84V L33F, N83ND, L89V L10I, K14R, K20KR, E35D, M36I, R41K, D60E, L63P, A71V, T91S, Q92QR, I93L  
>187443| codons 1-99
PQITLWQRPIVTIRIGGQLREALLDTGADDTVFEDINLPGKWKPKMIAGIGGFVKVRQYE
QIPIEICGHKVIGTVLVGPTPADVIGRNVLSRLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012