<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, L74I, M184V, T215Y K219E, N348I Y181I   K20R, V179I, I202V, E203K, Q207H, R211K, F214L, K223E, L228H, V245K, A272P, I293V, E297K, L310I, D324E, G359S, A371V, S379G, V381I, I382V, K385KR, T386I, K390R  
>187220| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV
FAIKKKNSTRWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII
IQYVDDLYVGSDLEIGQHRTKVKELRHHLLKWGLYTPDEKHQEEPPFHWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTKEAE
LELAENREIIKEPVHGVYYDPSKELIAEIQKQGQGQWTYQIYQEPFKILKTGKYARMRSA
HTNDVKQLTEVVQKIATEGIIVWGRIPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, I84V, L90M G48E, L89V L10I, I13V, K20MT, E35D, M36I, R57K, Q61N, I62V, L63P, C67Y, G68E, H69Y, A71V, Q92K, I93L  
>187220| codons 1-99
PQITLWQRPIVTVKIGGQLTEALLDTGADDTVLEDINLPGRWKPKLIEGIGGFVKVKQYD
NVPIEIYEYKVIGTVLVGPTPVNVIGRNVMTKLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012