<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, V75M, M184I, L210W, T215Y F77L, N348I K101E, Y181C, G190S   E6D, V35T, T39A, E44D, V118I, K122E, I135V, T200K, Q207E, L228H, V245VM, A272P, T286A, A288T, E291D, E297K, I341F, R356K, G359S, K366R, K390R, Q394L, E399D  
>185006| codons 1-399
PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAELEKDGKISKIGPENPYNTPV
FAIKKKNSDKWRKLMDLRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
CQYIDDLYVSSDLEIGQHRKKIEELREHLWRWGFYTPDKKHQKEPPFHWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKTLTDVIPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQFYQEPFKILKTGKYAKMRSA
HTNDVRQLTEAVQKIATESIVIWGKTPKFRLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M   L10IV, I13IV, K14KR, I15V, K20T, E35N, M36I, P39PS, R41K, R57K, Q61N, I62V, L63P, I64IV, A71AT, T74S, I93L  
>185006| codons 1-99
PQITLWQRPVVTVRVGGQLTEALLDTGADDTVLENINLSGKWKPKMIGGIGGFIKVKQYD
NVPVEICGHKTIGSVLVGPTPVNIIGRNLMTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012