<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, V75M, L210W, T215Y K219R K103KN, G190A K238T P4PS, V35T, K43N, E44D, V60I, V118I, D123E, R211K, V245T, D250E, A272P, K281R, E297R, I329L, M357T, A376S, S379C, K390R, E399D  
>184334| codons 1-399
PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELENDGKISKIGPENPYNTPI
FAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLYVASDLEIGQHRTKIEELRQHLWKWGFYTPDRKHQKEPPFLWMGYELHPDTWT
VQPITLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTEVIPLTREAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGQGQWTYQIYQEPFKNLKTGKYARTRGA
HTNDVKQLTEAVQKISTECIVIWGKTPKFRLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, L90M   L10I, L19Q, K20R, E35D, M36I, N37NT, R41K, R57K, D60E, Q61D, I62V, L63P, A71V, I72T, V82I, I85V, I93L  
>184334| codons 1-99
PQITLWQRPIVTIKIGGQQREALLDTGADDTVLEDITLPGKWKPKMIVGIGGFIKVKQYE
DVPIEICGHKVTGTVLVGPTPINIVGRNLMTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012