<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, L210W, T215F   L100I, K103N   K20R, E44D, V60I, V118I, K122E, I135T, T200A, Q207N, R211S, F214FL, V245T, A272P, K277R, I293V, T296TS, E297KT, L303LM, Q334QR, Q340QH, M357MR, R358K, G359S, A371V, A376S, T386V, K390R, E399D  
>183006| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPI
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRAKIEELRNHLWSWGLFTPDKKHQKEPPFLWMGYELHPDKWT
VQPITLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLSTEAE
LEMAENREILKEPVHGVYYDPSKDLIAEIQKQGRGQWTYHIYQEPFKNLKTGKYARRKSA
HTNDVKQLTEVVQKISTESIVIWGKVPKFRLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82T, L90M G73S L10I, K20R, E35D, M36I, N37DE, R41K, R57RK, I62V, L63P, A71T, I72K, Q92E, I93L  
>183006| codons 1-99
PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDIELPGKWKPKIIGGIGGFVKVKQYD
QVPIEICGHKTKSTVLVGPTPTNIIGRNLMTELGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012