<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L210W, T215Y V75M Y188YFHL, G190AS   V35T, K43Q, E44D, V60I, K101Q, V118I, D123E, I142Q, T200A, E203D, Q207E, R211K, E248ED, A272P, K281R, T286P, I293V, E297K, D324E, R358K, K366KR, I375V, A376S, K390R, E399D  
>182090| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEQDGKISKIGPENPYNTPI
FAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSIPL
DKEFRKYTAFTIPSINNETPGQRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLLVSSDLEIGQHRAKIDELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGPKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMKGA
HTNDVRQLTEAVQKVSTESIVIWGKTPKFRLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V L89V E35N, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, A71T, T74S, V82I, Q92K K20P
>182090| codons 19-99
LPEALLDTGADDTVLENIDLPGKWKPKIIGGIGGFVKVKQYDNVPIEICGHKTIGSVVVG
PTPINIIGRNVLTKIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012