<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, T215F K219Q, N348I L100I, K103N   V90I, I142IT, T165I, T200V, L228LH, E248D, K277KR, Q278QH, T286A, E312Q, D324E, M357T, A376S, T377S, T386I, K390R, I393M, E399EK, A400S  
>181668| codons 2-400
ISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVF
AIKKKNSTRWRKLVDFRELNKRTQDFWEIQLGIPHPAGIKKNKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIGQHRVKIEELRQHLLRWGFFTPDQKHQKEPPFHWMGYELHPDKWTV
QPIVLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVRHLCKLLRGAKALTEVIPLTEEAEL
ELAENREILKQPVHGVYYDPSKELIAEIQKQGQGQWTYQIYQEPFKILKTGKYARTRGAH
TNDVKQLTEAVQKISSESIVIWGKIPKFRLPMQKETWKS

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, L90M G73T L10I, I13V, L19I, K55R, I62V, L63P, H69R, I72V, V77I  
>181668| codons 1-99
PQITLWQRPIVTVKIGGQIKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIRVRQYD
QVPIEICGRKAVTTVLIGPTPVNIIGRNLMTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012