<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V     V179D K20R, L34I, T39A, V118I, K122E, I135T, T165I, Q207H, L210S, R211K, F214L, V245M, A272P, K277R, E297K, I341V, A376S, T386I, K390R, E399EK  
>181449| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKAIVEICAEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKQNPDIDI
YQYVDDLYVGSDLEIGQHRTKIEELRHHLSKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQVYQEPFKNLKTGKYARMRGA
HTNDVKQLTEAVQKISTESIVIWGKIPKFRLPIQKETWK

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, I54V, V82A, L90M   L10I, K14R, L19IV, I62V, L63P, A71IV, V77I, Q92E, I93M  
>181449| codons 1-99
PQITLWQRPIVTIRIGGQVKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFVKVRQYD
QVPIEICGHKVIGTVLIGPTPANIIGRNLMTEMGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012