<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y   K101E, Y181C V108I P4Q, V35M, K43N, A98S, D123E, I135V, S162C, V179I, R211K, D237E, E248D, K277R, Q278H, T286A, I293V, E297K, D324E, I329L, Q334E, M357MIT, A360T, K390R E138T
>181333| codons 1-398
PISQIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICTELENEGKISKIGPENPYNTPV
FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPSGLEKKKSVTILDVGDAYFSVPL
DKEFRKYTAFTIPSVNNTTPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIII
CQYVDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPEKWT
VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVRHLCKLLRGAKALTEVVPLTKEAE
LELAENREILKEPVHGVYYDPSKELIAELQKQGEGQWTYQIYQEPFKNLKTGKYARTRGT
HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46L, I47V, I54M, V82A, I84IV L24I, K43T L10Y, I15V, G16E, L19I, K20R, E35D, M36I, I62IV, L63C, I64V, A71V, V77VI  
>181333| codons 1-99
PQITLWQRPYVTIKVEGQIREALIDTGADDTILEDINLPGRWTPKLVGGIGGFMKVRQYD
QVCVEICGHKVIGTVLIGPTPANVIGRNLLTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012