<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, L210W, T215Y V75S, K219E K101E, Y181C, G190A   V35I, T39A, L109I, V118I, K122E, I135V, S162A, R211X, D218E, L228H, V245KM, A272P, K277R, T286A, T296S, E297A, I326V, R358K, G359S, T369V, A376I, T386M, K390KR P140T
>180939| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICAELEKEGKISKIGPENPYNTPV
FAIKKKNSTRWRKLSDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVIDVGDAYFSIPL
DEDFRKYTAFTIPSVNNETTGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPDIVI
CQYMDDLYVASDLEIGQHRTKIEELRQHLWXWGFYTPEEKHQKEPPFHWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVIPLSAEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMKSA
HTNDVKQLVEAVQKIITESIVIWGKMPKFRLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I54V, V82T, L90M F53L, Q58E, G73S L10I, L19LV, K20R, M36I, D60E, I62V, L63P, A71V, I72L, I85IV  
>180939| codons 1-99
PQITLWQRPIVTIKIGGQVREALLDTGADDTVLEEINLPGRWKPKIIGGIGGLVKVREYE
QVPIEICGHKVLSTVLVGPTPTNIVGRNLMTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012