<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V T215I, K219E, N348I G190S   V21VI, V35T, E40D, K49KR, I50IV, I135IT, K173I, Q174K, G196E, Q197QH, V245M, A272P, K281R, A288S, V292I, E297R, Q334N, G335S, T338S, M357T, R358K, K366R, A376AT, T377L, T386I, K390R, E399D  
>180532| codons 1-399
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTDMEKEGKISRVGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPDIVI
YQYVDDLYVSSDLEIEHHRTKIEELRQHLLRWGFITPDEKHQKEPPFLWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKSLTEIIPLTREAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGNSQWSYQIYQEPFKILKTGKYARTKGA
HTNDVRQLTEAVQKITLESIVIWGKIPKFRLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T4TA, I15V, E35D, M36I, N37NY, R41K, V56VI, R57K, Q61N, L63G, H69Q, V77I  
>180532| codons 1-99
PQIALWQRPLVTIKVGGQLKEALLDTGADDTVLEDIYLPGKWKPKMIGGIGGFIKIKQYD
NIGIEICGQKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012