Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| JS3 | JS98471 | Luxembourg | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | NA |
| 2 | 3TC+AZT+IDV | 24 |
| 3 | 3TC+D4T+IDV | 12 |
| 4 | 3TC+AZT+IDV | 24 |
| 5 | NVP+3TC+D4T | 48 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, T215Y | K103N | A98S, D123E, I135L, I178M, R211K, D250T |
| >JS98471| codons 25-252 PLTEEKIKALVEICTELEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKRT QDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSLNNETPGIRY QYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVIYQYVDDLYVGSDLEIGQHRTKIEE LRQHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKTSW |
References
| Author | Title | Citation |
| Servais, J | Comparison of DNA sequencing and a line probe assay for detection of human immunodeficiency virus type 1 drug resistance mutations in patients failing highly active antiretroviral therapy. | J Clin Microbiol, 2001 |
| Gonzales, MJ | Extended spectrum of HIV-1 reverse transcriptase mutations in patients receiving multiple nucleoside analog inhibitors. | AIDS, 2003 |
| Gonzales, MJ | Protease and reverse transcriptase mutation patterns in HIV-1 isolates from heavily treated persons: comparison of isolates from northern California with isolates from other regions. | ARHR, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |