<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, D67N, T69DN, K70R, T215Y K219E, N348I K103N V108I, L234LI K20R, E28K, V35IT, T39A, E40D, V60I, K122E, D123E, I135T, D177E, L228H, A272P, K275R, P294S, E297K, Q334H, G335S, R356K, G359S, A376T, T386A, Q394L, E399D  
>179613| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTKEKIKALTEICADLEKEGKISKIGPENPYNTPI
FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL
DEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI
YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFYTPDEKHQKEPPFHWMGYEIHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGTKALTEVISLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHSQWTYQIYQEPFKILKTGKYAKMRSA
HTNDVKQLTEAVQKITTESIVIWGKAPKFKLPILKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, L90M F53L L10I, I15V, G16E, K20R, E35D, M36I, N37T, R41K, R57K, Q61N, L63T, E65D, I72T, V77I  
>179613| codons 1-99
PQITLWQRPIVTIKVEGQLREALLDTGADDTVLEDITLPGKWKPKMIGGIGGLVKVKQYD
NITIDICGHKATGTVLIGPTPANIIGRNLMTQIGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012