<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, D67DN, T69D, L74V, L210W T215C L100I, K103N A98AG, V108VI K20R, V35IT, K43KN, E44ED, V118VI, D121H, K122E, K166KR, Q174QR, D177E, I178L, V179VI, H208HY, R211K, E248D, A272P, K277R, K281KR, A288AT, I293V, E297R, A360AV, K366R, A376AT, T386I, E399D  
>179490| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTELENDGKISKIGPENPYNTPV
FAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHPGGIKKNKSVTILDVGDAYFSIPL
HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKRNPELII
YQYMDDLYVGSDLEIGQHRTKIEELRQYLWKWGFCTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCRLLRGTKTLTEVVPLTREAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGV
HTNDVRQLTEAVQKITTESIVIWGKIPKFKLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A, L90M L33F, K43T L10I, I13IV, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, I64L, A71T, I72T, I93L  
>179490| codons 1-99
PQITLWQRPIVTVKVGGQLREALLDTGADDTVFEDINLPGKWTPKLIGGIGGFVRVKQYD
NVPLEICGHKTTGTVLVGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Jones, LR Drug resistance mutations in HIV pol sequences from Argentinean patients under antiretroviral treatment: subtype, gender, and age issues. ARHR, 2012